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1

MDM2 SNP309 genotype is associated with ferritin and LDH serum levels in children with stage 4 neuroblastoma

Stefano Parodi, Chiara Perfumo, Alberto Garaventa, Alberto Inga, Katia Mazzocco, Raffaella Defferrari, Gian Paolo Tonini, Gilberto Fronza, Riccardo Haupt

Journal:

Pediatric Blood & Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 136 KB

english, 2010

2

Characterization of the p53 mutants ability to inhibit p73β transactivation using a yeast-based functional assay

Monti, Paola, Campomenosi, Paola, Ciribilli, Yari, Iannone, Raffaella, Aprile, Anna, Inga, Alberto, Tada, Mitsuhiro, Menichini, Paola, Abbondandolo, Angelo, Fronza, Gilberto

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 175 KB

english, 2003

3

Heterogeneous p53 mutations in a Burkitt lymphoma from an AIDS patient with monoclonal c-myc and VDJ rearrangements

Paola Campomenosi, Gilberto Fronza, Laura Ottaggio, Silvio Roncella, Alberto Inga, Massimo Bogliolo, Paola Monti, Paola Assereto, Francesca Moro, Giovanna Cutrona, Simonetta Bozzo, Nicholas Chiorazzi,

Journal:

International Journal of Cancer

Année:

1997

Langue:

english

Fichier:

PDF, 159 KB

english, 1997

4

Mutational specificity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in Escherichia coli: Comparison of in vivo with in vitro exposure of the supF gene

Francisco L. Luque-Romero, Raffaella Iannone, Alberto Inga, Gilberto Fronza, Carmen Pueyo

Journal:

Environmental and Molecular Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 78 KB

english, 1997

5

Mutation spectra analysis suggests that N-(2-chloroethyl)-N′-cyclohexyl-N-nitrosourea-induced lesions are subject to transcription-coupled repair in Escherichia coli

Raffaella Iannone, Alberto Inga, Francisco L. Luque-Romero, Paola Menichini, Angelo Abbondandolo, Nieves Abril, Carmen Pueyo, Gilberto Fronza

Journal:

Molecular Carcinogenesis

Année:

1997

Langue:

english

Fichier:

PDF, 115 KB

english, 1997

6

Analysis of stepwise genetic changes in an AIDS-related Burkitt's lymphoma

Franco Fais, Gilberto Fronza, Silvio Roncella, Alberto Inga, Paola Campomenosi, Giovanna Cutrona, Annalisa Pezzolo, Franco Fedeli, Angelo Abbondandolo, Nicholas Chiorazzi, Vito Pistoia, Manlio Ferrari

Journal:

International Journal of Cancer

Année:

2000

Langue:

english

Fichier:

PDF, 200 KB

english, 2000

7

Partial characterization of SUVi, a new mammalian gene induced by UV-c and expressed during the S phase of the cell cycle

Silvia Viaggi, Elena Gallerani, Francesco Molina, Michael Nuesse, Gilberto Fronza, Laura Ottaggio, Paola Campomenosi, Angelo Abbondandolo, Paola Menichini

Journal:

Environmental and Molecular Mutagenesis

Année:

2001

Langue:

english

Fichier:

PDF, 247 KB

english, 2001

8

The biological effects of N3-methyladenine

Gilberto Fronza, Barry Gold

Journal:

Journal of Cellular Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 122 KB

english, 2004

9

Stable formation of mutated p53 multimers in a Chinese hamster cell line causes defective p53 nuclear localization and abrogates its residual function

Laura Ottaggio, Paola Campomenosi, Gilberto Fronza, Paola Menichini, Mariangela Miele, Francesca Moro, Silvia Viaggi, Annalisa Zunino, Angelo Abbondandolo

Journal:

Journal of Cellular Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 290 KB

english, 2006

10

The kinetics of p53-binding and histone acetylation at target promoters do not strictly correlate with gene expression after UV damage

Roberta Magrini, Debora Russo, Gilberto Fronza, Alberto Inga, Paola Menichini

Journal:

Journal of Cellular Biochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 306 KB

english, 2007

11

Identification of a novel TP53 germline mutation in a large Italian Li—Fraumeni syndrome Family

Valeria Capra, Alessandro Consales, Paola Nozza, Paola Monti, Alberto Inga, Gilberto Fronza

Journal:

Pediatric Blood & Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 81 KB

english, 2009

12

MDM2 SNP309 genotype influences survival of metastatic but not of localized neuroblastoma

Chiara Perfumo, Stefano Parodi, Katia Mazzocco, Raffaella Defferrari, Alberto Inga, Giovanna Bianchi Scarrà, Paola Ghiorzo, Riccardo Haupt, Gian Paolo Tonini, Gilberto Fronza

Journal:

Pediatric Blood & Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 133 KB

english, 2009

13

Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology

Inga, Alberto, Iannone, Raffaella, Monti, Paola, Molina, Francesco, Bolognesi, Martino, Abbondandolo, Angelo, Iggo, Richard, Fronza, Gilberto

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 916 KB

english, 1997

14

p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay

Inga, Alberto, Monti, Paola, Fronza, Gilberto, Darden, Tom, Resnick, Michael A

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 552 KB

english, 2001

15

Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay

Maurici, Daniela, Monti, Paola, Campomenosi, Paola, North, Sophie, Frebourg, Thierry, Fronza, Gilberto, Hainaut, Pierre

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 706 KB

english, 2001

16

Tumour p53 mutations exhibit promoter selective dominance over wild type p53

Monti, Paola, Campomenosi, Paola, Ciribilli, Yari, Iannone, Raffaella, Inga, Alberto, Abbondandolo, Angelo, Resnick, Michael A, Fronza, Gilberto

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 195 KB

english, 2002

17

Lack of mutations in K-ras codons 12 and 13 in human atherosclerotic lesions

Massimo Bogliolo, Gilberto Fronza, Paola Campomenosi, Paola Assereto, Alberto Izzotti, Gian Luigi Petrilli, Angelo Abbondandolo, Silvio De Flora

Journal:

Chemico-Biological Interactions

Année:

1996

Langue:

english

Fichier:

PDF, 549 KB

english, 1996

18

Mutation spectrum of 4-nitroquinoline 1-oxide-damaged single-stranded shuttle vector DNA transfected into monkey cells

Gilberto Fronza, Catherine Madzak, Paola Campomenosi, Alberto Inga, Raffaella Iannone, Angelo Abbondandolo, Alain Sarasin

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1994

Langue:

english

Fichier:

PDF, 756 KB

english, 1994

19

Concentration-dependent mutational hotspots induced by the antineoplastic drug chloroethyl-cyclohexyl-nitroso-urea in mammalian cells

Gilberto Fronza, Alberto Inga, Raffaella Iannone, Angelo Abbondandolo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1996

Langue:

english

Fichier:

PDF, 252 KB

english, 1996

20

Defective splicing induced by 4NQO in the hamster hprt gene

Paola Menichini, Alberto Inga, Gilberto Fronza, Raffaella Iannone, Paolo Degan, Paola Campomenosi, Angelo Abbondandolo

Journal:

Mutation Research Letters

Année:

1994

Langue:

english

Fichier:

PDF, 548 KB

english, 1994

21

Rev1 and Polζ influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent

Paola Monti, Yari Ciribilli, Debora Russo, Alessandra Bisio, Chiara Perfumo, Virginia Andreotti, Paola Menichini, Alberto Inga, Xiaofen Huang, Barry Gold, Gilberto Fronza

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 343 KB

english, 2008

22

XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine

Debora Russo, Gilberto Fronza, Laura Ottaggio, Paola Monti, Chiara Perfumo, Alberto Inga, Prema Iyer, Barry Gold, Paola Menichini

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 450 KB

english, 2010

23

3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro

Paola Monti, Christopher Broxson, Alberto Inga, Ruo-wen Wang, Paola Menichini, Silvia Tornaletti, Barry Gold, Gilberto Fronza

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 513 KB

english, 2011

24

Mutagenicity of N3-methyladenine: A multi-translesion polymerase affair

Paola Monti, Ilaria Traverso, Laura Casolari, Paola Menichini, Alberto Inga, Laura Ottaggio, Debora Russo, Prema Iyer, Barry Gold, Gilberto Fronza

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2010

Langue:

english

Fichier:

PDF, 288 KB

english, 2010

25

High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells

Debora Russo, Gilberto Fronza, Laura Ottaggio, Paola Monti, Alberto Inga, Prema Iyer, Barry Gold, Paola Menichini

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2009

Langue:

english

Fichier:

PDF, 381 KB

english, 2009

26

P VII.3 - P VII.3 A gene trap approach to isolate DNA damage inducible genes: Cloning of a new gene involved in the cellular response to genotoxic stress

Paola Menichini, Silvia Viaggi, Elena Gallerani, Alberto Comes, Annalisa Zunino, Gilberto Fronza, Laura Ottaggio, Joackim Ellwart, Angelo Abbondandolo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 130 KB

english, 1997

27

P XI A.8 - P XI A.8 A gene trap approach to isolate DNA damage inducible genes: Cloning of a new gene involved in the cellular response to genotoxic stress

Paola Menichini, Silvia Viaggi, Elena Gallerani, Alberto Comes, Annalisa Zunino, Gilberto Fronza, Laura Ottaggio, Joackim Ellwart, Angelo Abbondandolo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 128 KB

english, 1997

28

P XII.10 - P XII.10 Trans-dominance analysis of p53 mutants by a yeast functional assay

Gilberto Fronza, Alberto Inga, Sara Cresta, Paola Monti, Anna Aprile, Richard Iggo, Angelo Abbondandolo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 131 KB

english, 1997

29

P XI A.10 - P XI A.10 Trans-dominance analysis of p53 mutants by a yeast functional assay

Gilberto Fronza, Alberto Inga, Sara Cresta, Paola Monti, Anna Aprile, Richard Iggo, Angelo Abbondandolo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 127 KB

english, 1997

30

P XI A.9 - P XI A.9 Carcinogen specific mutational fingerprints at the human p53 locus with a yeast functional assay

Alberto Inga, Paola Monti, Sara Cresta, Anna Aprile, Gina Scott, Angelo Abbondandolo, Phil Burns, Gilberto Fronza

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 127 KB

english, 1997

31

5-Methylcytosine at HpaII sites in p53 is not hypermutable after UVC irradiation

Paola Monti, Alberto Inga, Gina Scott, Anna Aprile, Paola Campomenosi, Paola Menichini, Laura Ottaggio, Silvia Viaggi, Angelo Abbondandolo, Philip A. Burns, Gilberto Fronza

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1999

Langue:

english

Fichier:

PDF, 597 KB

english, 1999

32

DNA adducts and chronic degenerative diseases. Pathogenetic relevance and implications in preventive medicine

Silvio De Flora, Alberto Izzotti, Kurt Randerath, Erika Randerath, Helmut Bartsch, Jagadeesan Nair, Roumen Balansky, Frederikjan van Schooten, Paolo Degan, Gilberto Fronza, Debra Walsh, Joellen Lewtas

Journal:

Mutation Research/Reviews in Genetic Toxicology

Année:

1996

Langue:

english

Fichier:

PDF, 1.67 MB

english, 1996

33

Derivative Chromosome 17 in a Case of Burkitt Lymphoma with 8;14 Translocation

Laura Ottaggio, Francesca Moro, Gilberto Fronza, Silvio Roncella, Simonetta Bozzo, Paola Campomenosi, Alberto Inga, Manlio Ferranini, Angelo Abbondandolo

Journal:

Cancer Genetics and Cytogenetics

Année:

1999

Langue:

english

Fichier:

PDF, 2.11 MB

english, 1999

34

PRIMA-1 cytotoxicity correlates with nucleolar localization and degradation of mutant p53 in breast cancer cells

Debora Russo, Laura Ottaggio, Ilaria Penna, Giorgia Foggetti, Gilberto Fronza, Alberto Inga, Paola Menichini

Journal:

Biochemical and Biophysical Research Communications

Année:

2010

Langue:

english

Fichier:

PDF, 496 KB

english, 2010

35

The yeast p53 functional assay: a new tool for molecular epidemiology. Hopes and facts

Gilberto Fronza, Alberto Inga, Paola Monti, Gina Scott, Paola Campomenosi, Paola Menichini, Laura Ottaggio, Silvia Viaggi, Philip A Burns, Barry Gold, Angelo Abbondandolo

Journal:

Mutation Research/Reviews in Mutation Research

Année:

2000

Langue:

english

Fichier:

PDF, 88 KB

english, 2000

36

DNA Damage and Cytotoxicity Induced by Minor Groove Binding Methyl Sulfonate Esters †

Varadarajan, Sridhar, Shah, Dharini, Dande, Prasad, Settles, Samuel, Chen, Fa-xian, Fronza, Gilberto, Gold, Barry

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 227 KB

english, 2003

37

Extent of helix perturbation associated with DNA modification by the o-acetyl derivative of the carcinogen 4-hydroxyaminoquinoline-1-oxide

Gilberto Fronza, Silvia Tornaletti, Paola Menichini, Sylvie Galiègue-Zouitina, Bernard Bailleul, Marie-H. Loucheux-Lefebvre, Angelo Abbondandolo, Antonia M. Pedrini

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1990

Langue:

english

Fichier:

PDF, 603 KB

english, 1990

38

PRIMA-1 induces autophagy in cancer cells carrying mutant or wild type p53

Russo, Debora, Ottaggio, Laura, Foggetti, Giorgia, Masini, Matilde, Masiello, Pellegrino, Fronza, Gilberto, Menichini, Paola

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2013

39

Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: Clarifying the role of N3-methyladenine

Monti, Paola, Foggetti, Giorgia, Menichini, Paola, Inga, Alberto, Gold, Barry, Fronza, Gilberto

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2014

Langue:

english

Fichier:

PDF, 773 KB

english, 2014

40

Evidence in Escherichia coli that N3-Methyladenine Lesions Induced by a Minor Groove Binding Methyl Sulfonate Ester Can Be Processed by both Base and Nucleotide Excision Repair †

Shah, Dharini, Kelly, Jack, Zhang, Yi, Dande, Prasad, Martinez, Juan, Ortiz, Gretchen, Fronza, Gilberto, Tran, Huy, Soto, Ana Maria, Marky, Luis, Gold, Barry

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 114 KB

english, 2001

41

Nucleotide Excision Repair Defect Influences Lethality and Mutagenicity Induced by Me-lex, a Sequence-Selective N 3-Adenine Methylating Agent in the Absence of Base Excision Repair †

Monti, Paola, Iannone, Raffaella, Campomenosi, Paola, Ciribilli, Yari, Varadarajan, Sridhar, Shah, Dharini, Menichini, Paola, Gold, Barry, Fronza, Gilberto

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 100 KB

english, 2004

42

Studying p53 family proteins in yeast: Induction of autophagic cell death and modulation by interactors and small molecules

Leão, Mariana, Gomes, Sara, Bessa, Cláudia, Soares, Joana, Raimundo, Liliana, Monti, Paola, Fronza, Gilberto, Pereira, Clara, Saraiva, Lucília

Journal:

Experimental Cell Research

Année:

2015

Langue:

english

Fichier:

PDF, 733 KB

english, 2015

43

Evidence in Escherichia coli that N3-Methyladenine Lesions Induced by a Minor Groove Binding Methyl Sulfonate Ester Can Be Processed by both Base and Nucleotide Excision Repair,

Shah, Dharini, Kelly, Jack, Zhang, Yi, Dande, Prasad, Martinez, Juan, Ortiz, Gretchen, Fronza, Gilberto, Tran, Huy, Soto, Ana Maria, Marky, Luis, Gold, Barry

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 23 KB

english, 2001

44

TP53 Mutants in the Tower of Babel of Cancer Progression

Bisio, Alessandra, Ciribilli, Yari, Fronza, Gilberto, Inga, Alberto, Monti, Paola

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 700 KB

english, 2014

45

Increased Risk of Colorectal Adenomas in Italian Subjects Carrying the p53 PIN3 A2-Pro72 Haplotype

Perfumo, Chiara, Bonelli, Luigina, Menichini, Paola, Inga, Alberto, Gismondi, Viviana, Ciferri, Enrico, Percivale, Pierluigi, Bianchi Scarr&agrave, , Giovanna, Nasti, Sabina, Fronza, Gilberto, Varesco,

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 161 KB

english, 2006

46

The 4-nitroquinoline 1-oxide mutational spectrum in single stranded DNA is characterized by guanine to pyrimidine transversions

Fronza, Gilberto, Campomenosi, Paola, lannone, Raffaella, Abbondandolo, Angelo

Journal:

Nucleic Acids Research

Année:

1992

Langue:

english

Fichier:

PDF, 455 KB

english, 1992

47

Analysis of 4-nitroquinoline-1-oxide induced mutations at the hprt locus in mammalian cells: possible involvement of preferential DNA repair

Inga, Alberto, Iannone, Raffaella, Degan, Paolo, Campomenosi, Paola, Fronza, Gilberto, Abbondandolo, Angelo, Menichini, Paola

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 682 KB

english, 1994

48

Human transcription factors in yeast: the fruitful examples of P53 and NF-кB

Sharma, Vasundhara, Monti, Paola, Fronza, Gilberto, Inga, Alberto

Journal:

FEMS Yeast Research

Année:

2016

Langue:

english

Fichier:

PDF, 729 KB

english, 2016

49

Gambogic acid counteracts mutant p53 stability by inducing autophagy

Foggetti, Giorgia, Ottaggio, Laura, Russo, Debora, Monti, Paola, Degan, Paolo, Fronza, Gilberto, Menichini, Paola

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2016

Langue:

english

Fichier:

PDF, 1015 KB

english, 2016

50

p53 Transactivation and the Impact of Mutations, Cofactors and Small Molecules Using a Simplified Yeast-Based Screening System

Andreotti, Virginia, Ciribilli, Yari, Monti, Paola, Bisio, Alessandra, Lion, Mattia, Jordan, Jennifer, Fronza, Gilberto, Menichini, Paola, Resnick, Michael A., Inga, Alberto, Santos, Janine

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2011